Mice Lacking M1 and M3 Muscarinic Acetylcholine Receptors Have Impaired Odor Discrimination and Learning

The cholinergic system has extensive projections to the olfactory bulb (OB) where it produces a state-dependent regulation of sensory gating. Previous work has shown a prominent role of muscarinic acetylcholine (ACh) receptors (mAChRs) in regulating the excitability of OB neurons, in particular the...

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Detalles Bibliográficos
Autores principales: Chan, Wilson, Singh, Sanmeet, Keshav, Taj, Dewan, Ramita, Eberly, Christian, Maurer, Robert, Nunez-Parra, Alexia, Araneda, Ricardo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288360/
https://www.ncbi.nlm.nih.gov/pubmed/28210219
http://dx.doi.org/10.3389/fnsyn.2017.00004

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