Increased Apoptosis in the Paraventricular Nucleus Mediated by AT1R/Ras/ERK1/2 Signaling Results in Sympathetic Hyperactivity and Renovascular Hypertension in Rats after Kidney Injury

Background: The central nervous system plays a vital role in the development of hypertension, but the molecular regulatory mechanisms are not fully understood. This study aimed to explore signaling in the paraventricular nucleus (PVN) which might contribute to renal hypertension. Methods: Renal hype...

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Detalles Bibliográficos
Autores principales: Zhu, Hongguo, Tan, Lishan, Li, Yumin, Li, Jiawen, Qiu, Minzi, Li, Lanying, Zhang, Mengbi, Liang, Min, Li, Aiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288364/
https://www.ncbi.nlm.nih.gov/pubmed/28210225
http://dx.doi.org/10.3389/fphys.2017.00041

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