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Kinetics of Cytotoxic Lymphocytes Reconstitution after Induction Chemotherapy in Elderly AML Patients Reveals Progressive Recovery of Normal Phenotypic and Functional Features in NK Cells

NK cells are defective in acute myeloid leukemia (AML) at diagnosis. Here, we studied the kinetic of expression of the major activating and inhibitory receptors of NK, CD8 T, and γδ T cells in patients undergoing chemotherapy (CT) for the treatment of AML (n = 29). We showed that NK cells are the ma...

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Detalles Bibliográficos
Autores principales: Rey, Jérôme, Fauriat, Cyril, Kochbati, Eloïse, Orlanducci, Florence, Charbonnier, Aude, D’Incan, Evelyne, Andre, Pascale, Romagne, François, Barbarat, Bernadette, Vey, Norbert, Olive, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288405/
https://www.ncbi.nlm.nih.gov/pubmed/28210257
http://dx.doi.org/10.3389/fimmu.2017.00064