DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression

Activated platelets generate an eicosanoid proposed to be 8-hydroxy-9,10-dioxolane A3 (DXA(3)). Herein, we demonstrate that significant amounts of DXA(3) are rapidly attached to phosphatidylethanolamine (PE) forming four esterified eicosanoids, 16:0p, 18:0p, 18:1p and 18:0a/DXA(3)-PEs that can activ...

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Detalles Bibliográficos
Autores principales: Aldrovandi, Maceler, Hinz, Christine, Lauder, Sarah N., Podmore, Helen, Hornshaw, Martin, Slatter, David A., Tyrrell, Victoria J., Clark, Stephen R., Marnett, Lawrence J., Collins, Peter W., Murphy, Robert C., O’Donnell, Valerie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288459/
https://www.ncbi.nlm.nih.gov/pubmed/28160743
http://dx.doi.org/10.1016/j.redox.2017.01.001

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