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Additive amelioration of ALS by co‐targeting independent pathogenic mechanisms

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which glia are central mediators of motor neuron (MN) death. Since multiple cell types are involved in disease pathogenesis, the objective of this study was to determine the benefit of co‐targeting independent pat...

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Detalles Bibliográficos
Autores principales: Frakes, Ashley E., Braun, Lyndsey, Ferraiuolo, Laura, Guttridge, Denis C., Kaspar, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288461/
https://www.ncbi.nlm.nih.gov/pubmed/28168207
http://dx.doi.org/10.1002/acn3.375