Cargando…
Extended and direct evaluation of RT‐QuIC assays for Creutzfeldt‐Jakob disease diagnosis
Real‐Time Quaking‐Induced Conversion (RT‐QuIC) testing of human cerebrospinal fluid (CSF) is highly sensitive and specific in discriminating sporadic CJD patients from those without prion disease. Here, using CSF samples from 113 CJD and 64 non‐prion disease patients, we provide the first direct and...
Autores principales: | Groveman, Bradley R., Orrú, Christina D., Hughson, Andrew G., Bongianni, Matilde, Fiorini, Michele, Imperiale, Daniele, Ladogana, Anna, Pocchiari, Maurizio, Zanusso, Gianluigi, Caughey, Byron |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288466/ https://www.ncbi.nlm.nih.gov/pubmed/28168213 http://dx.doi.org/10.1002/acn3.378 |
Ejemplares similares
-
Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid
por: Orrú, Christina D., et al.
Publicado: (2015) -
Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product
por: Raymond, Gregory J., et al.
Publicado: (2020) -
Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD
por: Orrú, Christina D., et al.
Publicado: (2020) -
Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues
por: Luk, Collin C., et al.
Publicado: (2021) -
Factors That Improve RT-QuIC Detection of Prion Seeding Activity
por: Orrú, Christina D., et al.
Publicado: (2016)