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Granzyme B; the chalk-mark of a cytotoxic lymphocyte
During cytotoxic lymphocyte (CL) mediated killing of target cells, granzyme B is released from the CL into the immune synapse. Recent studies have found that ELISPOT-detection of granzyme B correlated well with conventional assays for CL mediated killing. In this way, the released granzyme B can be...
Autores principales: | Waterhouse, Nigel J, Sedelies, Karin A, Clarke, Chris JP |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC528853/ https://www.ncbi.nlm.nih.gov/pubmed/15500699 http://dx.doi.org/10.1186/1479-5876-2-36 |
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