Cargando…
Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps
OBJECTIVE: Whereas few adenomas become cancer, most colorectal cancers arise from adenomas. Telomere length is a recognized biomarker in multiple cancers, and telomere maintenance mechanisms (TMM) are exploited by malignant cells. We sought to determine whether telomere length and TMM distinguish ca...
Autores principales: | Druliner, Brooke R, Ruan, Xiaoyang, Johnson, Ruth, Grill, Diane, O'Brien, Daniel, Lai, Tsung-Po, Rashtak, Shahrooz, Felmlee-Devine, Donna, Washechek-Aletto, Jill, Malykh, Andrei, Smyrk, Thomas, Oberg, Ann, Liu, Hongfang, Shay, Jerry W, Ahlquist, David A, Boardman, Lisa A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288594/ https://www.ncbi.nlm.nih.gov/pubmed/27584834 http://dx.doi.org/10.1038/ctg.2016.48 |
Ejemplares similares
-
Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps
por: Druliner, Brooke R, et al.
Publicado: (2017) -
Colorectal Cancer with Residual Polyp of Origin: A Model of Malignant Transformation()()
por: Druliner, Brooke R., et al.
Publicado: (2016) -
Colonoscopy surveillance for high risk polyps does not always prevent colorectal cancer
por: Mouchli, Mohamad A, et al.
Publicado: (2018) -
Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations
por: Druliner, Brooke R., et al.
Publicado: (2018) -
Inferring modes of evolution from colorectal cancer with residual polyp of origin
por: Kim, Minsoo, et al.
Publicado: (2017)