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Time Lapse to Colorectal Cancer: Telomere Dynamics Define the Malignant Potential of Polyps
OBJECTIVE: Whereas few adenomas become cancer, most colorectal cancers arise from adenomas. Telomere length is a recognized biomarker in multiple cancers, and telomere maintenance mechanisms (TMM) are exploited by malignant cells. We sought to determine whether telomere length and TMM distinguish ca...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288594/ https://www.ncbi.nlm.nih.gov/pubmed/27584834 http://dx.doi.org/10.1038/ctg.2016.48 |
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por Druliner, Brooke R, Ruan, Xiaoyang, Johnson, Ruth, Grill, Diane, O'Brien, Daniel, Lai, Tsung-Po, Rashtak, Shahrooz, Felmlee-Devine, Donna, Washechek-Aletto, Jill, Malykh, Andrei, Smyrk, Thomas, Oberg, Ann, Liu, Hongfang, Shay, Jerry W, Ahlquist, David A, Boardman, Lisa A
Publicado 2017
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Publicado 2017
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Online
Artículo
Texto