Deletion of the Ste20-like kinase SLK in skeletal muscle results in a progressive myopathy and muscle weakness

BACKGROUND: The Ste20-like kinase, SLK, plays an important role in cell proliferation and cytoskeletal remodeling. In fibroblasts, SLK has been shown to respond to FAK/Src signaling and regulate focal adhesion turnover through Paxillin phosphorylation. Full-length SLK has also been shown to be essen...

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Detalles Bibliográficos
Autores principales: Pryce, Benjamin R., Al-Zahrani, Khalid N., Dufresne, Sébastien, Belkina, Natalya, Labrèche, Cédrik, Patino-Lopez, Genaro, Frenette, Jérôme, Shaw, Stephen, Sabourin, Luc A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288853/
https://www.ncbi.nlm.nih.gov/pubmed/28153048
http://dx.doi.org/10.1186/s13395-016-0119-1

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