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Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

BACKGROUND: Here we integrate verified signals from previous genetic association studies with gene expression and pathway analysis for discovery of new candidate genes and signaling networks, relevant for rheumatoid arthritis (RA). METHOD: RNA-sequencing-(RNA-seq)-based expression analysis of 377 ge...

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Detalles Bibliográficos
Autores principales: Shchetynsky, Klementy, Diaz-Gallo, Lina-Marcella, Folkersen, Lasse, Hensvold, Aase Haj, Catrina, Anca Irinel, Berg, Louise, Klareskog, Lars, Padyukov, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288892/
https://www.ncbi.nlm.nih.gov/pubmed/28148290
http://dx.doi.org/10.1186/s13075-017-1220-5

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