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Limb salvage with microvascular free fibula following primary bone sarcoma resection

BACKGROUND: Extremity sarcomas are challenging to manage. Total eradication of tumour has to be balanced with restoration of limb function to prevent mortality and morbidity. Disease-free survival with maximum limb function is the ultimate goal in these patients. MATERIALS AND METHODS: We present a...

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Autores principales: Parag, Sahasrabudhe, Yogesh, Panchwagh, Rathod, Jesal, Nikhil, Panse, Amit, Jadhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288913/
https://www.ncbi.nlm.nih.gov/pubmed/28216818
http://dx.doi.org/10.4103/0970-0358.197244
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author Parag, Sahasrabudhe
Yogesh, Panchwagh
Rathod, Jesal
Nikhil, Panse
Amit, Jadhav
author_facet Parag, Sahasrabudhe
Yogesh, Panchwagh
Rathod, Jesal
Nikhil, Panse
Amit, Jadhav
author_sort Parag, Sahasrabudhe
collection PubMed
description BACKGROUND: Extremity sarcomas are challenging to manage. Total eradication of tumour has to be balanced with restoration of limb function to prevent mortality and morbidity. Disease-free survival with maximum limb function is the ultimate goal in these patients. MATERIALS AND METHODS: We present a series of ten cases of extremity malignancies, where limb salvage was attempted with microvascular free fibula for limb reconstruction from the period of 2008 to 2015. RESULTS: Of the ten cases in the study, there were two females and eight males. There were nine patients with lower limb malignancies and one patient with upper limb malignancy. There were four patients with Ewing's sarcoma of femur, five patients with osteosarcoma of femur and one patient with chondrosarcoma of the humerus. The follow-up period ranged from 1.2 to 6.2 years with mean follow-up of 3.1 years. There were two deaths during follow-up, both were due to distant metastasis. The assessment of the function was done on the basis of Musculoskeletal Tumour Society functional score. Maximum score was 30 and minimum score was 24, the average score being 26. Of the eight surviving patients, three patients had full weightbearing, four patients had partial weightbearing at end of 2 years and one patient of upper limb reconstruction had complete upper limb function. None of the patients had to undergo limb amputation. CONCLUSION: Limb salvage with vascularised fibula graft offers good functional outcome along with good disease-free survival rates.
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spelling pubmed-52889132017-02-17 Limb salvage with microvascular free fibula following primary bone sarcoma resection Parag, Sahasrabudhe Yogesh, Panchwagh Rathod, Jesal Nikhil, Panse Amit, Jadhav Indian J Plast Surg Original Article BACKGROUND: Extremity sarcomas are challenging to manage. Total eradication of tumour has to be balanced with restoration of limb function to prevent mortality and morbidity. Disease-free survival with maximum limb function is the ultimate goal in these patients. MATERIALS AND METHODS: We present a series of ten cases of extremity malignancies, where limb salvage was attempted with microvascular free fibula for limb reconstruction from the period of 2008 to 2015. RESULTS: Of the ten cases in the study, there were two females and eight males. There were nine patients with lower limb malignancies and one patient with upper limb malignancy. There were four patients with Ewing's sarcoma of femur, five patients with osteosarcoma of femur and one patient with chondrosarcoma of the humerus. The follow-up period ranged from 1.2 to 6.2 years with mean follow-up of 3.1 years. There were two deaths during follow-up, both were due to distant metastasis. The assessment of the function was done on the basis of Musculoskeletal Tumour Society functional score. Maximum score was 30 and minimum score was 24, the average score being 26. Of the eight surviving patients, three patients had full weightbearing, four patients had partial weightbearing at end of 2 years and one patient of upper limb reconstruction had complete upper limb function. None of the patients had to undergo limb amputation. CONCLUSION: Limb salvage with vascularised fibula graft offers good functional outcome along with good disease-free survival rates. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5288913/ /pubmed/28216818 http://dx.doi.org/10.4103/0970-0358.197244 Text en Copyright: © Indian Journal of Plastic Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Parag, Sahasrabudhe
Yogesh, Panchwagh
Rathod, Jesal
Nikhil, Panse
Amit, Jadhav
Limb salvage with microvascular free fibula following primary bone sarcoma resection
title Limb salvage with microvascular free fibula following primary bone sarcoma resection
title_full Limb salvage with microvascular free fibula following primary bone sarcoma resection
title_fullStr Limb salvage with microvascular free fibula following primary bone sarcoma resection
title_full_unstemmed Limb salvage with microvascular free fibula following primary bone sarcoma resection
title_short Limb salvage with microvascular free fibula following primary bone sarcoma resection
title_sort limb salvage with microvascular free fibula following primary bone sarcoma resection
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288913/
https://www.ncbi.nlm.nih.gov/pubmed/28216818
http://dx.doi.org/10.4103/0970-0358.197244
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