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Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer
BACKGROUND: ADAM12 is upregulated in human breast cancers and is a predictor of chemoresistance in estrogen receptor-negative tumors. ADAM12 is induced during epithelial-to-mesenchymal transition, a feature associated with claudin-low breast tumors, which are enriched in cancer stem cell (CSC) marke...
Autores principales: | Duhachek-Muggy, Sara, Qi, Yue, Wise, Randi, Alyahya, Linda, Li, Hui, Hodge, Jacob, Zolkiewska, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288940/ https://www.ncbi.nlm.nih.gov/pubmed/28148288 http://dx.doi.org/10.1186/s12943-017-0599-6 |
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