TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer

BACKGROUND: Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the potential contribution of ovarian cancer genomic instability resulted from TP...

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Detalles Bibliográficos
Autores principales: Zhang, Meiying, Zhuang, Guanglei, Sun, Xiangjun, Shen, Yanying, Wang, Wenjing, Li, Qing, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288946/
https://www.ncbi.nlm.nih.gov/pubmed/28148293
http://dx.doi.org/10.1186/s13000-017-0605-8

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