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Higher mortality risk among injured individuals in a population-based matched cohort study

BACKGROUND: Improved understanding of long-term mortality attributable to injury is needed to accurately inform injury burden studies. This study aims to quantify and describe mortality attributable to injury 12 months after an injury-related hospitalisation in Australia. METHOD: A population-based...

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Autores principales: Mitchell, Rebecca J., Cameron, Cate M., McClure, Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288995/
https://www.ncbi.nlm.nih.gov/pubmed/28148259
http://dx.doi.org/10.1186/s12889-017-4087-0
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author Mitchell, Rebecca J.
Cameron, Cate M.
McClure, Rod
author_facet Mitchell, Rebecca J.
Cameron, Cate M.
McClure, Rod
author_sort Mitchell, Rebecca J.
collection PubMed
description BACKGROUND: Improved understanding of long-term mortality attributable to injury is needed to accurately inform injury burden studies. This study aims to quantify and describe mortality attributable to injury 12 months after an injury-related hospitalisation in Australia. METHOD: A population-based matched cohort study using linked hospital and mortality data from three Australian states during 2008–2010 was conducted. The injured cohort included individuals ≥18 years who had an injury-related hospital admission in 2009. A comparison cohort of non-injured people was obtain by randomly selecting from the electoral roll. This comparison group was matched 1:1 on age, gender and postcode of residence. Pre-index injury health service use and 12-month mortality were examined. Adjusted mortality rate ratios (MRR) and attributable risk were calculated. Cox proportional hazard regression was used to examine the effect of risk factors on survival. RESULTS: Injured individuals were almost 3 times more likely to die within 12 months following an injury (MRR 2.90; 95% CI: 2.76–3.04). Individuals with a traumatic brain injury (MRR 7.58; 95% CI: 5.92–9.70) or injury to internal organs (MRR 7.38; 95% CI: 5.90–9.22) were 7 times more likely to die than the non-injured group. Injury was likely to be a contributory factor in 92% of mortality within 30 days and 66% of mortality at 12 months following the index injury hospital admission. Adjusted mortality rate ratios varied by type of cause-specific death, with MRR highest for injury-related deaths. CONCLUSIONS: There are likely chronic consequences of sustaining a traumatic injury. Longer follow-up post-discharge is needed to consider deaths likely to be attributable to the injury. Better enumeration of long-term injury-related mortality will have the potential to improve estimates of injury burden.
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spelling pubmed-52889952017-02-09 Higher mortality risk among injured individuals in a population-based matched cohort study Mitchell, Rebecca J. Cameron, Cate M. McClure, Rod BMC Public Health Research Article BACKGROUND: Improved understanding of long-term mortality attributable to injury is needed to accurately inform injury burden studies. This study aims to quantify and describe mortality attributable to injury 12 months after an injury-related hospitalisation in Australia. METHOD: A population-based matched cohort study using linked hospital and mortality data from three Australian states during 2008–2010 was conducted. The injured cohort included individuals ≥18 years who had an injury-related hospital admission in 2009. A comparison cohort of non-injured people was obtain by randomly selecting from the electoral roll. This comparison group was matched 1:1 on age, gender and postcode of residence. Pre-index injury health service use and 12-month mortality were examined. Adjusted mortality rate ratios (MRR) and attributable risk were calculated. Cox proportional hazard regression was used to examine the effect of risk factors on survival. RESULTS: Injured individuals were almost 3 times more likely to die within 12 months following an injury (MRR 2.90; 95% CI: 2.76–3.04). Individuals with a traumatic brain injury (MRR 7.58; 95% CI: 5.92–9.70) or injury to internal organs (MRR 7.38; 95% CI: 5.90–9.22) were 7 times more likely to die than the non-injured group. Injury was likely to be a contributory factor in 92% of mortality within 30 days and 66% of mortality at 12 months following the index injury hospital admission. Adjusted mortality rate ratios varied by type of cause-specific death, with MRR highest for injury-related deaths. CONCLUSIONS: There are likely chronic consequences of sustaining a traumatic injury. Longer follow-up post-discharge is needed to consider deaths likely to be attributable to the injury. Better enumeration of long-term injury-related mortality will have the potential to improve estimates of injury burden. BioMed Central 2017-02-02 /pmc/articles/PMC5288995/ /pubmed/28148259 http://dx.doi.org/10.1186/s12889-017-4087-0 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mitchell, Rebecca J.
Cameron, Cate M.
McClure, Rod
Higher mortality risk among injured individuals in a population-based matched cohort study
title Higher mortality risk among injured individuals in a population-based matched cohort study
title_full Higher mortality risk among injured individuals in a population-based matched cohort study
title_fullStr Higher mortality risk among injured individuals in a population-based matched cohort study
title_full_unstemmed Higher mortality risk among injured individuals in a population-based matched cohort study
title_short Higher mortality risk among injured individuals in a population-based matched cohort study
title_sort higher mortality risk among injured individuals in a population-based matched cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288995/
https://www.ncbi.nlm.nih.gov/pubmed/28148259
http://dx.doi.org/10.1186/s12889-017-4087-0
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