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The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity

Deregulated metabolism is a well-established hallmark of cancer. At the hub of various metabolic pathways deeply integrated within mitochondrial functions, the α-ketoglutarate dehydrogenase complex represents a major modulator of electron transport chain activity and tricarboxylic acid cycle (TCA) f...

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Detalles Bibliográficos
Autores principales:	Vatrinet, Renaud, Leone, Giulia, De Luise, Monica, Girolimetti, Giulia, Vidone, Michele, Gasparre, Giuseppe, Porcelli, Anna Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289018/ https://www.ncbi.nlm.nih.gov/pubmed/28184304 http://dx.doi.org/10.1186/s40170-017-0165-0

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