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Synthesis and biological evaluation of the new 1,3-dimethylxanthine derivatives with thiazolidine-4-one scaffold

BACKGROUND: The xanthine structure has proved to be an important scaffold in the process of developing a wide variety of biologically active molecules such as bronchodilator, hypoglycemiant, anticancer and anti-inflammatory agents. It is known that hyperglycemia generates reactive oxygen species whi...

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Detalles Bibliográficos
Autores principales: Constantin, Sandra, Lupascu, Florentina Geanina, Apotrosoaei, Maria, Vasincu, Ioana Mirela, Lupascu, Dan, Buron, Frederic, Routier, Sylvain, Profire, Lenuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289128/
https://www.ncbi.nlm.nih.gov/pubmed/28203273
http://dx.doi.org/10.1186/s13065-017-0241-0