Cargando…

miR-21 increases c-kit(+) cardiac stem cell proliferation in vitro through PTEN/PI3K/Akt signaling

The low survival rate of cardiac stem cells (CSCs) in the ischemic myocardium is one of the obstacles in ischemic cardiomyopathy cell therapy. The MicroRNA (miR)-21 and one of its target protein, the tensin homolog deleted on chromosome ten (PTEN), contributes to the proliferation of many kinds of t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Bei, Deng, Wenwen, Long, Xianping, Zhao, Ranzun, Wang, Yan, Chen, Wenming, Xu, Guanxue, Sheng, Jin, Wang, Dongmei, Cao, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2017
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289448/ https://www.ncbi.nlm.nih.gov/pubmed/28168101 http://dx.doi.org/10.7717/peerj.2859

Ejemplares similares

miR-21 Reduces Hydrogen Peroxide-Induced Apoptosis in c-kit(+) Cardiac Stem Cells In Vitro through PTEN/PI3K/Akt Signaling
por: Deng, Wenwen, et al.
Publicado: (2016)

Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit(+) cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis
por: Shi, Bei, et al.
Publicado: (2018)

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice
por: Sun, Chen, et al.
Publicado: (2014)

Exosomes Derived from miR-214-Enriched Bone Marrow-Derived Mesenchymal Stem Cells Regulate Oxidative Damage in Cardiac Stem Cells by Targeting CaMKII
por: Wang, Yan, et al.
Publicado: (2018)

CircHIPK3 regulates cardiac fibroblast proliferation, migration and phenotypic switching through the miR-152-3p/TGF-β2 axis under hypoxia
por: Liu, Weiwei, et al.
Publicado: (2020)

Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn’s disease
por: Xie, Xiaoran, et al.
Publicado: (2022)

Matrine regulates H(2)O(2)-induced oxidative stress through long non-coding RNA HOTAIR/miR-106b-5p axis via AKT and STAT3 pathways
por: Xu, Guanxue, et al.
Publicado: (2020)

Honokiol suppresses proliferation and induces apoptosis via regulation of the miR-21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells
por: Yang, Jiexiang, et al.
Publicado: (2018)

MiR-21 promotes pterygium cell proliferation through the PTEN/AKT pathway
por: Li, Xia, et al.
Publicado: (2018)

miR-21 promotes osteoclastogenesis through activation of PI3K/Akt signaling by targeting Pten in RAW264.7 cells
por: Wang, Shengli, et al.
Publicado: (2020)

Signal peptidase 21 suppresses cell proliferation, migration, and invasion via the PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma
por: Zhang, Na, et al.
Publicado: (2022)

USP25 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome by Modulating the PI3K/AKT Pathway via Deubiquitinating PTEN
por: Gao, Yue, et al.
Publicado: (2021)

MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer
por: Zheng, Lin, et al.
Publicado: (2015)

Per2 attenuates LPS-induced chondrocyte injury through the PTEN/PI3K/Akt signalling pathway
por: Zhao, Yu, et al.
Publicado: (2020)

miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling
por: Liu, Hongzhe, et al.
Publicado: (2014)

Effects of miR-21 on proliferation and apoptosis of WT cells via PTEN/Akt pathway
por: Zhang, Xiuli, et al.
Publicado: (2020)

miR-365 inhibits duck myoblast proliferation by targeting IGF-I via PI3K/Akt pathway
por: Sun, Wenqiang, et al.
Publicado: (2019)

miR-21 antagonist alleviates colitis and angiogenesis via the PTEN/PI3K/AKT pathway in colitis mice induced by TNBS
por: Xie, Xiaoran, et al.
Publicado: (2022)

miR-494 promotes progression of retinoblastoma via PTEN through PI3K/AKT signaling pathway
por: Xu, Fen, et al.
Publicado: (2020)

miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer
por: Liu, Jing, et al.
Publicado: (2017)

Cryptotanshinone Inhibites Bladder Cancer Cell Proliferation and Promotes Apoptosis via the PTEN/PI3K/AKT Pathway
por: Liu, Yadong, et al.
Publicado: (2020)

MiR-374b Promotes Proliferation and Inhibits Apoptosis of Human GIST Cells by Inhibiting PTEN through Activation of the PI3K/Akt Pathway
por: Long, Zi-Wen, et al.
Publicado: (2018)

Tetrandrine inhibits proliferation of colon cancer cells by BMP9/ PTEN/ PI3K/AKT signaling
por: Zhou, Ya, et al.
Publicado: (2019)

lncNALT knockdown ameliorates hypertensive retinopathy via PTEN/PI3K/AKT pathway
por: Kang, Haijun, et al.
Publicado: (2023)

IFN-τ mediated miR-26a targeting PTEN to activate PI3K/AKT signalling to alleviate the inflammatory damage of bEECs
por: Liu, Junfeng, et al.
Publicado: (2022)

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT
por: Zheng, Zhiming, et al.
Publicado: (2017)

MicroRNA‐4286 promotes cell proliferation, migration, and invasion via PTEN regulation of the PI3K/Akt pathway in non‐small cell lung cancer
por: Ling, Chunhua, et al.
Publicado: (2019)

SPAG6 promotes cell proliferation and inhibits apoptosis through the PTEN/PI3K/AKT pathway in Burkitt lymphoma
por: Zhang, Rongrong, et al.
Publicado: (2020)

PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN
por: Wang, Xuemei, et al.
Publicado: (2023)

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
por: Carnero, Amancio, et al.
Publicado: (2014)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

Antitumor activity of celastrol by inhibition of proliferation, invasion, and migration in cholangiocarcinoma via PTEN/PI3K/Akt pathway
por: Zhu, Biqiang, et al.
Publicado: (2019)

MiR-508-3p promotes proliferation and inhibits apoptosis of middle ear cholesteatoma cells by targeting PTEN/PI3K/AKT pathway
por: Liu, Dongliang, et al.
Publicado: (2021)

ClpP regulates breast cancer cell proliferation, invasion and apoptosis by modulating the Src/PI3K/Akt signaling pathway
por: Luo, Juan, et al.
Publicado: (2020)

Extracorporeal Cardiac Shock Wave-Induced Exosome Derived From Endothelial Colony-Forming Cells Carrying miR-140-3p Alleviate Cardiomyocyte Hypoxia/Reoxygenation Injury via the PTEN/PI3K/AKT Pathway
por: Yang, Dan, et al.
Publicado: (2022)

GPER1 Silencing Suppresses the Proliferation, Migration, and Invasion of Gastric Cancer Cells by Inhibiting PI3K/AKT–Mediated EMT
por: Xu, En, et al.
Publicado: (2020)

Knockdown of miR-214 Alleviates Renal Interstitial Fibrosis by Targeting the Regulation of the PTEN/PI3K/AKT Signalling Pathway
por: Hou, DongHua, et al.
Publicado: (2022)

PTENP1/miR-20a/PTEN axis contributes to breast cancer progression by regulating PTEN via PI3K/AKT pathway
por: Gao, Xue, et al.
Publicado: (2019)

Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway
por: Ma, Zhenling, et al.
Publicado: (2021)

PPA1 Promotes Breast Cancer Proliferation and Metastasis Through PI3K/AKT/GSK3β Signaling Pathway
por: Guo, Chunlei, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_dmc6hvkds5lqc1d89ubigdqdrr