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Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK
OBJECTIVES: To determine the effect of hyperopic laser in situ keratomileusis (H-LASIK) on corneal integrity, by investigating relationships between proportionate corneal tissue ablated and refractive outcomes at 3 months. METHODS: 18 eyes of 18 subjects treated with H-LASIK by Technolas 217c Excime...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289449/ https://www.ncbi.nlm.nih.gov/pubmed/28151939 http://dx.doi.org/10.1371/journal.pone.0170559 |
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author | Fatseas, George Stapleton, Fiona Versace, Patrick |
author_facet | Fatseas, George Stapleton, Fiona Versace, Patrick |
author_sort | Fatseas, George |
collection | PubMed |
description | OBJECTIVES: To determine the effect of hyperopic laser in situ keratomileusis (H-LASIK) on corneal integrity, by investigating relationships between proportionate corneal tissue ablated and refractive outcomes at 3 months. METHODS: 18 eyes of 18 subjects treated with H-LASIK by Technolas 217c Excimer Laser were included in the study. Orbscan II Topography System was used to determine corneal volume and pachymetry 3mm temporally (3T). The volume of corneal tissue ablated was determined from the laser nomogram. Univariate associations between age, treatment, corneal volume, overall proportion of tissue removed, proportion of tissue removed at 3T, residual bed thickness at 3T and refractive outcomes 3 months post-LASIK were examined and independent factors associated with refractive outcomes determined using linear regression models. RESULTS: At 3 months post-LASIK, the mean difference to expected refractive outcome was -0.20 ± 0.64 (Range -2.00 to +1.00). In univariate analysis, difference to expected refractive outcome was associated with proportion of tissue removed at 3T (P<0.01, r = -0.605) and total number of pulses (P< 0.05, r = -0.574). In multivariable analysis, difference to expected refractive outcome was associated with the proportion of tissue removed at 3T only. CONCLUSION: Subjects undergoing H-LASIK, may present as either over or under-corrected at 3 months. The proportion of tissue removed at 3T was the single significant determinant of this outcome, suggesting unexpected biomechanical alterations resulting in corneal steepening. Future hyperopic LASIK procedures could consider proportionate volume of corneal tissue removed at 3T in addition to laser nomograms to achieve improved refractive outcomes. |
format | Online Article Text |
id | pubmed-5289449 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-52894492017-02-17 Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK Fatseas, George Stapleton, Fiona Versace, Patrick PLoS One Research Article OBJECTIVES: To determine the effect of hyperopic laser in situ keratomileusis (H-LASIK) on corneal integrity, by investigating relationships between proportionate corneal tissue ablated and refractive outcomes at 3 months. METHODS: 18 eyes of 18 subjects treated with H-LASIK by Technolas 217c Excimer Laser were included in the study. Orbscan II Topography System was used to determine corneal volume and pachymetry 3mm temporally (3T). The volume of corneal tissue ablated was determined from the laser nomogram. Univariate associations between age, treatment, corneal volume, overall proportion of tissue removed, proportion of tissue removed at 3T, residual bed thickness at 3T and refractive outcomes 3 months post-LASIK were examined and independent factors associated with refractive outcomes determined using linear regression models. RESULTS: At 3 months post-LASIK, the mean difference to expected refractive outcome was -0.20 ± 0.64 (Range -2.00 to +1.00). In univariate analysis, difference to expected refractive outcome was associated with proportion of tissue removed at 3T (P<0.01, r = -0.605) and total number of pulses (P< 0.05, r = -0.574). In multivariable analysis, difference to expected refractive outcome was associated with the proportion of tissue removed at 3T only. CONCLUSION: Subjects undergoing H-LASIK, may present as either over or under-corrected at 3 months. The proportion of tissue removed at 3T was the single significant determinant of this outcome, suggesting unexpected biomechanical alterations resulting in corneal steepening. Future hyperopic LASIK procedures could consider proportionate volume of corneal tissue removed at 3T in addition to laser nomograms to achieve improved refractive outcomes. Public Library of Science 2017-02-02 /pmc/articles/PMC5289449/ /pubmed/28151939 http://dx.doi.org/10.1371/journal.pone.0170559 Text en © 2017 Fatseas et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Fatseas, George Stapleton, Fiona Versace, Patrick Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title | Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title_full | Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title_fullStr | Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title_full_unstemmed | Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title_short | Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK |
title_sort | role of percent peripheral tissue ablated on refractive outcomes following hyperopic lasik |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289449/ https://www.ncbi.nlm.nih.gov/pubmed/28151939 http://dx.doi.org/10.1371/journal.pone.0170559 |
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