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Superoxide dismutase/catalase mimetic EUK-134 prevents diaphragm muscle weakness in monocrotalin-induced pulmonary hypertension

Patients with pulmonary hypertension (PH) suffer from inspiratory insufficiency, which has been associated with intrinsic contractile dysfunction in diaphragm muscle. Here, we examined the role of redox stress in PH-induced diaphragm weakness by using the novel antioxidant, EUK-134. Male Wistar rats...

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Detalles Bibliográficos
Autores principales:	Himori, Koichi, Abe, Masami, Tatebayashi, Daisuke, Lee, Jaesik, Westerblad, Håkan, Lanner, Johanna T., Yamada, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289453/ https://www.ncbi.nlm.nih.gov/pubmed/28152009 http://dx.doi.org/10.1371/journal.pone.0169146

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