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Antigenic characterization of the human immunodeficiency virus (HIV-1) envelope glycoprotein precursor incorporated into nanodiscs
The entry of human immunodeficiency virus (HIV-1) into host cells is mediated by the viral envelope glycoproteins (Envs), which are derived by the proteolytic cleavage of a trimeric gp160 Env precursor. The mature Env trimer is a major target for entry inhibitors and vaccine-induced neutralizing ant...
Autores principales: | Witt, Kristen C., Castillo-Menendez, Luis, Ding, Haitao, Espy, Nicole, Zhang, Shijian, Kappes, John C., Sodroski, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289478/ https://www.ncbi.nlm.nih.gov/pubmed/28151945 http://dx.doi.org/10.1371/journal.pone.0170672 |
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