Cargando…
Microbiome sharing between children, livestock and household surfaces in western Kenya
The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289499/ https://www.ncbi.nlm.nih.gov/pubmed/28152044 http://dx.doi.org/10.1371/journal.pone.0171017 |
_version_ | 1782504505542180864 |
---|---|
author | Mosites, Emily Sammons, Matt Otiang, Elkanah Eng, Alexander Noecker, Cecilia Manor, Ohad Hilton, Sarah Thumbi, Samuel M. Onyango, Clayton Garland-Lewis, Gemina Call, Douglas R. Njenga, M. Kariuki Wasserheit, Judith N. Zambriski, Jennifer A. Walson, Judd L. Palmer, Guy H. Montgomery, Joel Borenstein, Elhanan Omore, Richard Rabinowitz, Peter M. |
author_facet | Mosites, Emily Sammons, Matt Otiang, Elkanah Eng, Alexander Noecker, Cecilia Manor, Ohad Hilton, Sarah Thumbi, Samuel M. Onyango, Clayton Garland-Lewis, Gemina Call, Douglas R. Njenga, M. Kariuki Wasserheit, Judith N. Zambriski, Jennifer A. Walson, Judd L. Palmer, Guy H. Montgomery, Joel Borenstein, Elhanan Omore, Richard Rabinowitz, Peter M. |
author_sort | Mosites, Emily |
collection | PubMed |
description | The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples from children and cattle, cloacal swabs from chickens, and swabs of household surfaces. Among the 156 households studied, children within the same household significantly shared their gut microbiome with each other, although we did not find significant sharing of gut microbiome across host species or household surfaces. Higher gut microbiome diversity among children was associated with lower wealth status and involvement in livestock feeding chores. Although more research is necessary to identify further drivers of microbiota development, these results suggest that the household should be considered as a unit. Livestock activities, health and microbiome perturbations among an individual child may have implications for other children in the household. |
format | Online Article Text |
id | pubmed-5289499 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-52894992017-02-17 Microbiome sharing between children, livestock and household surfaces in western Kenya Mosites, Emily Sammons, Matt Otiang, Elkanah Eng, Alexander Noecker, Cecilia Manor, Ohad Hilton, Sarah Thumbi, Samuel M. Onyango, Clayton Garland-Lewis, Gemina Call, Douglas R. Njenga, M. Kariuki Wasserheit, Judith N. Zambriski, Jennifer A. Walson, Judd L. Palmer, Guy H. Montgomery, Joel Borenstein, Elhanan Omore, Richard Rabinowitz, Peter M. PLoS One Research Article The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples from children and cattle, cloacal swabs from chickens, and swabs of household surfaces. Among the 156 households studied, children within the same household significantly shared their gut microbiome with each other, although we did not find significant sharing of gut microbiome across host species or household surfaces. Higher gut microbiome diversity among children was associated with lower wealth status and involvement in livestock feeding chores. Although more research is necessary to identify further drivers of microbiota development, these results suggest that the household should be considered as a unit. Livestock activities, health and microbiome perturbations among an individual child may have implications for other children in the household. Public Library of Science 2017-02-02 /pmc/articles/PMC5289499/ /pubmed/28152044 http://dx.doi.org/10.1371/journal.pone.0171017 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication. |
spellingShingle | Research Article Mosites, Emily Sammons, Matt Otiang, Elkanah Eng, Alexander Noecker, Cecilia Manor, Ohad Hilton, Sarah Thumbi, Samuel M. Onyango, Clayton Garland-Lewis, Gemina Call, Douglas R. Njenga, M. Kariuki Wasserheit, Judith N. Zambriski, Jennifer A. Walson, Judd L. Palmer, Guy H. Montgomery, Joel Borenstein, Elhanan Omore, Richard Rabinowitz, Peter M. Microbiome sharing between children, livestock and household surfaces in western Kenya |
title | Microbiome sharing between children, livestock and household surfaces in western Kenya |
title_full | Microbiome sharing between children, livestock and household surfaces in western Kenya |
title_fullStr | Microbiome sharing between children, livestock and household surfaces in western Kenya |
title_full_unstemmed | Microbiome sharing between children, livestock and household surfaces in western Kenya |
title_short | Microbiome sharing between children, livestock and household surfaces in western Kenya |
title_sort | microbiome sharing between children, livestock and household surfaces in western kenya |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289499/ https://www.ncbi.nlm.nih.gov/pubmed/28152044 http://dx.doi.org/10.1371/journal.pone.0171017 |
work_keys_str_mv | AT mositesemily microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT sammonsmatt microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT otiangelkanah microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT engalexander microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT noeckercecilia microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT manorohad microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT hiltonsarah microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT thumbisamuelm microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT onyangoclayton microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT garlandlewisgemina microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT calldouglasr microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT njengamkariuki microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT wasserheitjudithn microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT zambriskijennifera microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT walsonjuddl microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT palmerguyh microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT montgomeryjoel microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT borensteinelhanan microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT omorerichard microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya AT rabinowitzpeterm microbiomesharingbetweenchildrenlivestockandhouseholdsurfacesinwesternkenya |