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Effect of pregabalin administration upon reperfusion in a rat model of hyperglycemic stroke: Mechanistic insights associated with high-mobility group box 1

Hyperglycemia, which reduces the efficacy of treatments and worsens clinical outcomes, is common in stroke. Ability of pregabalin to reduce neuroexcitotoxicity may provide protection against stroke, even under hyperglycemia. We investigated its protective effect against hyperglycemic stroke and its...

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Detalles Bibliográficos
Autores principales: Song, Young, Jun, Ji-Hae, Shin, Eun-Jung, Kwak, Young-Lan, Shin, Jeon-Soo, Shim, Jae-Kwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289503/
https://www.ncbi.nlm.nih.gov/pubmed/28152042
http://dx.doi.org/10.1371/journal.pone.0171147