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Bumetanide increases Cl(-)-dependent short-circuit current in late distal colon: Evidence for the presence of active electrogenic Cl(-) absorption

Mammalian colonic epithelia consist of cells that are capable of both absorbing and secreting Cl(-). The present studies employing Ussing chamber technique identified two opposing short-circuit current (I(sc)) responses to basolateral bumetanide in rat distal colon. Apart from the transepithelial Cl...

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Detalles Bibliográficos
Autores principales: Tang, Lieqi, Fang, Xiefan, Winesett, Steven P., Cheng, Catherine Y., Binder, Henry J., Rivkees, Scott A., Cheng, Sam X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289505/
https://www.ncbi.nlm.nih.gov/pubmed/28152000
http://dx.doi.org/10.1371/journal.pone.0171045