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Highly tumorigenic hepatocellular carcinoma cell line with cancer stem cell-like properties
There are limited numbers of models to study hepatocellular carcinoma (HCC) in vivo in immunocompetent hosts. In an effort to develop a cell line with improved tumorigenicity, we derived a new cell line from Hepa1-6 cells through an in vivo passage in C57BL/6 mice. The resulting Dt81Hepa1-6 cell lin...
Autores principales: | Lacoste, Benoit, Raymond, Valérie-Ann, Cassim, Shamir, Lapierre, Pascal, Bilodeau, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289561/ https://www.ncbi.nlm.nih.gov/pubmed/28152020 http://dx.doi.org/10.1371/journal.pone.0171215 |
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