Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation

It is now well established that both inherited and acquired forms of hemolytic disease can promote pulmonary vascular disease consequent of free hemoglobin (Hb) induced NO scavenging, elevations in reactive oxygen species and lipid peroxidation. It has recently been reported that oxidative stress ca...

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Detalles Bibliográficos
Autores principales: Loomis, Zoe, Eigenberger, Paul, Redinius, Katherine, Lisk, Christina, Karoor, Vijaya, Nozik-Grayck, Eva, Ferguson, Scott K., Hassell, Kathryn, Nuss, Rachelle, Stenmark, Kurt, Buehler, Paul, Irwin, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289566/
https://www.ncbi.nlm.nih.gov/pubmed/28152051
http://dx.doi.org/10.1371/journal.pone.0171219

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