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Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age
Accumulation of reactive oxygen species (ROS) is an important pathogenic mechanism underling the loss of bone mass and strength with aging and other conditions leading to osteoporosis. The transcription factor erythroid 2-related factor2 (Nrf2) plays a central role in activating the cellular respons...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289572/ https://www.ncbi.nlm.nih.gov/pubmed/28152064 http://dx.doi.org/10.1371/journal.pone.0171161 |