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GRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi Infection

BACKGROUND: Trypanosoma cruzi infection is associated with severe T cell unresponsiveness to antigens and mitogens and is characterized by decreased IL-2 synthesis. In addition, the acquisition of the anergic phenotype is correlated with upregulation of “gene related to anergy in lymphocytes” (GRAIL...

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Detalles Bibliográficos
Autores principales:	Stempin, Cinthia C., Rojas Marquez, Jorge D., Ana, Yamile, Cerban, Fabio M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289611/ https://www.ncbi.nlm.nih.gov/pubmed/28114324 http://dx.doi.org/10.1371/journal.pntd.0005307

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