Anaerobically Grown Escherichia coli Has an Enhanced Mutation Rate and Distinct Mutational Spectra

Oxidative stress is a major cause of mutation but little is known about how growth in the absence of oxygen impacts the rate and spectrum of mutations. We employed long-term mutation accumulation experiments to directly measure the rates and spectra of spontaneous mutation events in Escherichia coli...

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Detalles Bibliográficos
Autores principales: Shewaramani, Sonal, Finn, Thomas J., Leahy, Sinead C., Kassen, Rees, Rainey, Paul B., Moon, Christina D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289635/
https://www.ncbi.nlm.nih.gov/pubmed/28103245
http://dx.doi.org/10.1371/journal.pgen.1006570

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