Highly sensitive detection of a HER2 12-base pair duplicated insertion mutation in lung cancer using the Eprobe-PCR method

Somatic mutation in human epidermal growth factor receptor-related 2 gene (HER2) is one of the driver mutations in lung cancer. HER2 mutations are found in about 2% of lung adenocarcinomas (ADCs). Previous reports have been based mainly on diagnostic screening by Sanger sequencing or next-generation...

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Detalles Bibliográficos
Autores principales: Takase, Yoshiaki, Usui, Kengo, Shimizu, Kimihiro, Kimura, Yasumasa, Ichihara, Tatsuo, Ohkawa, Takahiro, Atsumi, Jun, Enokida, Yasuaki, Nakazawa, Seshiru, Obayashi, Kai, Ohtaki, Yoichi, Nagashima, Toshiteru, Mitani, Yasumasa, Takeyoshi, Izumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289711/
https://www.ncbi.nlm.nih.gov/pubmed/28152008
http://dx.doi.org/10.1371/journal.pone.0171225

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