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Recombinant Haplotypes Narrow the ARMS2/HTRA1 Association Signal for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in ageing societies, triggered by both environmental and genetic factors. The strongest genetic signal for AMD with odds ratios of up to 2.8 per adverse allele was found previously over a chromosomal region in 10q26 harboring t...

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Detalles Bibliográficos
Autores principales:	Grassmann, Felix, Heid, Iris M., Weber, Bernhard H. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2017
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289859/ https://www.ncbi.nlm.nih.gov/pubmed/27879347 http://dx.doi.org/10.1534/genetics.116.195966

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