Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression

Down syndrome (DS) is the leading chromosomal cause of intellectual disability, yet the neural substrates of learning and memory deficits remain poorly understood. Here, we interrogate neural networks linked to learning and memory in a well-characterized model of DS, the Ts65Dn mouse. We report that...

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Detalles Bibliográficos
Autores principales: Smith-Hicks, Constance L., Cai, Peiling, Savonenko, Alena V., Reeves, Roger H., Worley, Paul F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289947/
https://www.ncbi.nlm.nih.gov/pubmed/28217086
http://dx.doi.org/10.3389/fncir.2017.00006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289947/
https://www.ncbi.nlm.nih.gov/pubmed/28217086
http://dx.doi.org/10.3389/fncir.2017.00006

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