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Genomic Editing of Non-Coding RNA Genes with CRISPR/Cas9 Ushers in a Potential Novel Approach to Study and Treat Schizophrenia

Schizophrenia is a genetically related mental illness, in which the majority of genetic alterations occur in the non-coding regions of the human genome. In the past decade, a growing number of regulatory non-coding RNAs (ncRNAs) including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) have be...

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Detalles Bibliográficos
Autores principales: Zhuo, Chuanjun, Hou, Weihong, Hu, Lirong, Lin, Chongguang, Chen, Ce, Lin, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289958/
https://www.ncbi.nlm.nih.gov/pubmed/28217082
http://dx.doi.org/10.3389/fnmol.2017.00028