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Phenotypic Consequences In vivo and In vitro of Rearranging the P Gene of RABV HEP-Flury
Phosphoprotein (P) of the Rabies virus (RABV) is critically required for viral replication and pathogenicity. Here we manipulated infectious cDNA clones of the RABV HEP-Flury to translocate the P gene from its wild-type position 2 to 1, 3, or 4 in gene order, using an approach which left the viral n...
Autores principales: | Mei, Mingzhu, Long, Teng, Zhang, Qiong, Zhao, Jing, Tian, Qin, Peng, Jiaojiao, Luo, Jun, Wang, Yifei, Lin, Yingyi, Guo, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5289960/ https://www.ncbi.nlm.nih.gov/pubmed/28217116 http://dx.doi.org/10.3389/fmicb.2017.00120 |
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