Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency

Glioblastoma Multiforme (GBM) is characterized by high cancer cell heterogeneity and the presence of a complex tumor microenvironment. Those factors are a key obstacle for the treatment of this tumor type. To model the disease in mice, the current strategy is to grow GBM cells in serum-free non-adhe...

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Detalles Bibliográficos
Autores principales: Behnan, J, Stangeland, B, Hosainey, S A M, Joel, M, Olsen, T K, Micci, F, Glover, J C, Isakson, P, Brinchmann, J E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290038/
https://www.ncbi.nlm.nih.gov/pubmed/27345406
http://dx.doi.org/10.1038/onc.2016.230

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