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TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2(+) neutrophils

Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component of the tumor microenvironment. Our previous work demonstrated that tumor necrosis factor α (TNFα)-activated MSCs significantly promoted tumor growth. However, the role of TNFα-treated MSCs in tumor metastasis...

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Detalles Bibliográficos
Autores principales: Yu, P F, Huang, Y, Han, Y Y, Lin, L Y, Sun, W H, Rabson, A B, Wang, Y, Shi, Y F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290040/
https://www.ncbi.nlm.nih.gov/pubmed/27375023
http://dx.doi.org/10.1038/onc.2016.217