Cargando…

TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2(+) neutrophils

Mesenchymal stromal cells (MSCs) tend to infiltrate into tumors and form a major component of the tumor microenvironment. Our previous work demonstrated that tumor necrosis factor α (TNFα)-activated MSCs significantly promoted tumor growth. However, the role of TNFα-treated MSCs in tumor metastasis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, P F, Huang, Y, Han, Y Y, Lin, L Y, Sun, W H, Rabson, A B, Wang, Y, Shi, Y F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290040/ https://www.ncbi.nlm.nih.gov/pubmed/27375023 http://dx.doi.org/10.1038/onc.2016.217

Ejemplares similares

Downregulation of CXCL12 in mesenchymal stromal cells by TGFβ promotes breast cancer metastasis
por: Yu, P F, et al.
Publicado: (2017)

Tumour cell-derived exosomes endow mesenchymal stromal cells with tumour-promotion capabilities
por: Lin, L Y, et al.
Publicado: (2016)

Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
por: Shou, P, et al.
Publicado: (2016)

Tumour necrosis factor-alpha (TNFα) stimulates the growth of human bone marrow stromal cells
por: Rougier, F., et al.
Publicado: (1997)

Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b
por: Chen, Y, et al.
Publicado: (2017)

A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR
por: Lau, T-S, et al.
Publicado: (2017)

TNF‐α augments CXCR2 and CXCR3 to promote progression of renal cell carcinoma
por: Sun, Kuang‐Hui, et al.
Publicado: (2016)

TNF-α induces endothelial–mesenchymal transition promoting stromal development of pancreatic adenocarcinoma
por: Adjuto-Saccone, Marjorie, et al.
Publicado: (2021)

EVER2 protein binds TRADD to promote TNF-α-induced apoptosis
por: Gaud, G, et al.
Publicado: (2013)

Interleukin-8 and its receptor CXCR2 in the tumour microenvironment promote colon cancer growth, progression and metastasis
por: Lee, Y S, et al.
Publicado: (2012)

TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration
por: Gao, Y, et al.
Publicado: (2017)

Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2
por: Tancevski, Ivan, et al.
Publicado: (2014)

Regulation of Immunity via Multipotent Mesenchymal Stromal Cells
por: Rubtsov, Y. P., et al.
Publicado: (2012)

The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
por: Raccosta, Laura, et al.
Publicado: (2013)

On the origin and development of glioblastoma: multifaceted role of perivascular mesenchymal stromal cells
por: Ah-Pine, F., et al.
Publicado: (2023)

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors
por: Al-toub, Mashael, et al.
Publicado: (2019)

TNF-α-induced alterations in stromal progenitors enhance leukemic stem cell growth via CXCR2 signaling
por: Agarwal, Puneet, et al.
Publicado: (2021)

IL-6 and TNF-α promote metastasis of lung cancer by inducing epithelial-mesenchymal transition
por: Shang, Guan-Sheng, et al.
Publicado: (2017)

CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer
por: Hu, J. L., et al.
Publicado: (2019)

Divergent Metabolomic Signatures of TGFβ2 and TNFα in the Induction of Retinal Epithelial-Mesenchymal Transition
por: Ng, Pei Qin, et al.
Publicado: (2023)

Role of stromal-derived factor-1<alpha>/CXCR4 in neo-intimal repair
por: Sheng, J, et al.
Publicado: (2011)

Triple-Negative Breast Cancer Cells Recruit Neutrophils by Secreting TGF-β and CXCR2 Ligands
por: SenGupta, Shuvasree, et al.
Publicado: (2021)

LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis
por: Hou, P, et al.
Publicado: (2014)

The LPS-induced neutrophil recruitment into rat air pouches is mediated by TNFα: likely macrophage origin
por: Arreto, C-D., et al.
Publicado: (1997)

Stromal Derived Factor-1/CXCR4 Axis Involved in Bone Marrow Mesenchymal Stem Cells Recruitment to Injured Liver
por: Xiao Ling, Kuai, et al.
Publicado: (2016)

Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase
por: Gong, Lei, et al.
Publicado: (2013)

Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states
por: Yoshida, T, et al.
Publicado: (2014)

Effects of a dual inhibitor of TNF-α and IL-1 on lipopolysaccharide-induced lung injury in rats
por: Yoshinari, D, et al.
Publicado: (2001)

Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium
por: Munir, Hafsa, et al.
Publicado: (2016)

Chronic Inflammatory Demyelinating Polyneuropathy Following Anti-TNF-α Therapy With Infliximab for Crohn's Disease
por: Kamel, Amir Y., et al.
Publicado: (2016)

Enhanced myeloid differentiation factor 88 promotes tumor metastasis via induction of epithelial–mesenchymal transition in human hepatocellular carcinoma
por: Jia, R-J, et al.
Publicado: (2014)

Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo
por: Powell, Davalyn, et al.
Publicado: (2018)

Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis
por: Watanabe, Koji, et al.
Publicado: (2017)

Recruitment of Mesenchymal Stem Cells Into Prostate Tumors Promotes Metastasis
por: Jung, Younghun, et al.
Publicado: (2013)

Mesenchymal Stem/Stromal Cells: HUMAN MESENCHYMAL STEM CELL THERAPY IN SEVERE COVID-19 PATIENTS: 2-YEAR FOLLOW-UP RESULTS OF A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
por: Li, T., et al.
Publicado: (2023)

Molecular Crosstalk Between Macrophages and Mesenchymal Stromal Cells
por: Stevens, Hazel Y., et al.
Publicado: (2020)

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
por: Hernandez, Lorena, et al.
Publicado: (2011)

Hyaluronan promotes intracellular ROS production and apoptosis in TNFα-stimulated neutrophils
por: Niemietz, Iwona, et al.
Publicado: (2023)

TNF-α/NF-κB/Snail pathway in cancer cell migration and invasion
por: Wu, Y, et al.
Publicado: (2010)

Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model
por: Yang, F, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_isq1kfq01r0f6bsthf713h20ap