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Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study

PURPOSE: Mediterranean-type dietary pattern has been associated with lower risk of cardiovascular (CVD) and other chronic diseases, primarily in Southern European populations. We examined whether Mediterranean diet score (MDS) is associated with total, CVD, coronary heart disease (CHD) and stroke mo...

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Autores principales: Stefler, Denes, Malyutina, Sofia, Kubinova, Ruzena, Pajak, Andrzej, Peasey, Anne, Pikhart, Hynek, Brunner, Eric J., Bobak, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290049/
https://www.ncbi.nlm.nih.gov/pubmed/26578528
http://dx.doi.org/10.1007/s00394-015-1092-x
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author Stefler, Denes
Malyutina, Sofia
Kubinova, Ruzena
Pajak, Andrzej
Peasey, Anne
Pikhart, Hynek
Brunner, Eric J.
Bobak, Martin
author_facet Stefler, Denes
Malyutina, Sofia
Kubinova, Ruzena
Pajak, Andrzej
Peasey, Anne
Pikhart, Hynek
Brunner, Eric J.
Bobak, Martin
author_sort Stefler, Denes
collection PubMed
description PURPOSE: Mediterranean-type dietary pattern has been associated with lower risk of cardiovascular (CVD) and other chronic diseases, primarily in Southern European populations. We examined whether Mediterranean diet score (MDS) is associated with total, CVD, coronary heart disease (CHD) and stroke mortality in a prospective cohort study in three Eastern European populations. METHODS: A total of 19,333 male and female participants of the Health Alcohol and Psychosocial factors in Eastern Europe (HAPIEE) study in the Czech Republic, Poland and the Russian Federation were included in the analysis. Diet was assessed by food frequency questionnaire, and MDS was derived from consumption of nine groups of food using absolute cut-offs. Mortality was ascertained by linkage with death registers. RESULTS: Over the median follow-up time of 7 years, 1314 participants died. The proportion of participants with high adherence to Mediterranean diet was low (25 %). One standard deviation (SD) increase in the MDS (equivalent to 2.2 point increase in the score) was found to be inversely associated with death from all causes (HR, 95 % CI 0.93, 0.88–0.98) and CVD (0.90, 0.81–0.99) even after multivariable adjustment. Inverse but statistically not significant link was found for CHD (0.90, 0.78–1.03) and stroke (0.87, 0.71–1.07). The MDS effects were similar in each country cohort. CONCLUSION: Higher adherence to the Mediterranean diet was associated with reduced risk of total and CVD deaths in these large Eastern European urban populations. The application of MDS with absolute cut-offs appears suitable for non-Mediterranean populations. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00394-015-1092-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-52900492017-02-16 Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study Stefler, Denes Malyutina, Sofia Kubinova, Ruzena Pajak, Andrzej Peasey, Anne Pikhart, Hynek Brunner, Eric J. Bobak, Martin Eur J Nutr Original Contribution PURPOSE: Mediterranean-type dietary pattern has been associated with lower risk of cardiovascular (CVD) and other chronic diseases, primarily in Southern European populations. We examined whether Mediterranean diet score (MDS) is associated with total, CVD, coronary heart disease (CHD) and stroke mortality in a prospective cohort study in three Eastern European populations. METHODS: A total of 19,333 male and female participants of the Health Alcohol and Psychosocial factors in Eastern Europe (HAPIEE) study in the Czech Republic, Poland and the Russian Federation were included in the analysis. Diet was assessed by food frequency questionnaire, and MDS was derived from consumption of nine groups of food using absolute cut-offs. Mortality was ascertained by linkage with death registers. RESULTS: Over the median follow-up time of 7 years, 1314 participants died. The proportion of participants with high adherence to Mediterranean diet was low (25 %). One standard deviation (SD) increase in the MDS (equivalent to 2.2 point increase in the score) was found to be inversely associated with death from all causes (HR, 95 % CI 0.93, 0.88–0.98) and CVD (0.90, 0.81–0.99) even after multivariable adjustment. Inverse but statistically not significant link was found for CHD (0.90, 0.78–1.03) and stroke (0.87, 0.71–1.07). The MDS effects were similar in each country cohort. CONCLUSION: Higher adherence to the Mediterranean diet was associated with reduced risk of total and CVD deaths in these large Eastern European urban populations. The application of MDS with absolute cut-offs appears suitable for non-Mediterranean populations. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00394-015-1092-x) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2015-11-17 2017 /pmc/articles/PMC5290049/ /pubmed/26578528 http://dx.doi.org/10.1007/s00394-015-1092-x Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Contribution
Stefler, Denes
Malyutina, Sofia
Kubinova, Ruzena
Pajak, Andrzej
Peasey, Anne
Pikhart, Hynek
Brunner, Eric J.
Bobak, Martin
Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title_full Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title_fullStr Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title_full_unstemmed Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title_short Mediterranean diet score and total and cardiovascular mortality in Eastern Europe: the HAPIEE study
title_sort mediterranean diet score and total and cardiovascular mortality in eastern europe: the hapiee study
topic Original Contribution
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290049/
https://www.ncbi.nlm.nih.gov/pubmed/26578528
http://dx.doi.org/10.1007/s00394-015-1092-x
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