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Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

The surrounding microenvironment limits tumour expansion, imposing a compressive stress on the tumour, but little is known how pressure propagates inside the tumour. Here we present non-destructive cell-like microsensors to locally quantify mechanical stress distribution in three-dimensional tissue....

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Detalles Bibliográficos
Autores principales: Dolega, M. E., Delarue, M., Ingremeau, F., Prost, J., Delon, A., Cappello, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290143/
https://www.ncbi.nlm.nih.gov/pubmed/28128198
http://dx.doi.org/10.1038/ncomms14056