mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis

Alternatively activated macrophages (M2) have an important function in innate immune responses to parasitic helminths, and emerging evidence also indicates these cells are regulators of systemic metabolism. Here we show a critical role for mTORC2 signalling in the generation of M2 macrophages. Abrog...

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Detalles Bibliográficos
Autores principales: Hallowell, R. W., Collins, S. L., Craig, J. M., Zhang, Y., Oh, M., Illei, P. B., Chan-Li, Y., Vigeland, C. L., Mitzner, W., Scott, A. L., Powell, J. D., Horton, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290163/
https://www.ncbi.nlm.nih.gov/pubmed/28128208
http://dx.doi.org/10.1038/ncomms14208

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