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Influence of Escherichia coli chaperone DnaK on protein immunogenicity

The production of anti‐drug antibodies can impact significantly upon the safety and efficacy of biotherapeutics. It is known that various factors, including aggregation and the presence of process‐related impurities, can modify and augment the immunogenic potential of proteins. The purpose of the in...

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Detalles Bibliográficos
Autores principales:	Ratanji, Kirsty D., Derrick, Jeremy P., Kimber, Ian, Thorpe, Robin, Wadhwa, Meenu, Dearman, Rebecca J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290234/ https://www.ncbi.nlm.nih.gov/pubmed/27859059 http://dx.doi.org/10.1111/imm.12689

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