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Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

Prostate-specific antigen (PSA) levels have been used for detection and surveillance of prostate cancer (PCa). However, factors other than PCa—such as genetics—can impact PSA. Here we present findings from a genome-wide association study (GWAS) of PSA in 28,503 Kaiser Permanente whites and 17,428 me...

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Detalles Bibliográficos
Autores principales: Hoffmann, Thomas J., Passarelli, Michael N., Graff, Rebecca E., Emami, Nima C., Sakoda, Lori C., Jorgenson, Eric, Habel, Laurel A., Shan, Jun, Ranatunga, Dilrini K., Quesenberry, Charles P., Chao, Chun R., Ghai, Nirupa R., Aaronson, David, Presti, Joseph, Nordström, Tobias, Wang, Zhaoming, Berndt, Sonja I., Chanock, Stephen J., Mosley, Jonathan D., Klein, Robert J., Middha, Mridu, Lilja, Hans, Melander, Olle, Kvale, Mark N., Kwok, Pui-Yan, Schaefer, Catherine, Risch, Neil, Van Den Eeden, Stephen K., Witte, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290311/
https://www.ncbi.nlm.nih.gov/pubmed/28139693
http://dx.doi.org/10.1038/ncomms14248

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