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Brain structure and intragenic DNA methylation are correlated, and predict executive dysfunction in fragile X premutation females
DNA methylation of the Fragile X mental retardation 1 (FMR1) exon 1/intron 1 boundary has been associated with executive dysfunction in female carriers of a FMR1 premutation (PM: 55–199 CGG repeats), whereas neuroanatomical changes have been associated with executive dysfunction in PM males. To our...
Autores principales: | Shelton, A L, Cornish, K M, Kolbe, S, Clough, M, Slater, H R, Li, X, Kraan, C M, Bui, Q M, Godler, D E, Fielding, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290342/ https://www.ncbi.nlm.nih.gov/pubmed/27959330 http://dx.doi.org/10.1038/tp.2016.250 |
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