Clozapine modifies the differentiation program of human adipocytes inducing browning

Administration of second-generation antipsychotic drugs (SGAs) often leads to weight gain and consequent cardio-metabolic side effects. We observed that clozapine but not six other antipsychotic drugs reprogrammed the gene expression pattern of differentiating human adipocytes ex vivo, leading to an...

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Detalles Bibliográficos
Autores principales: Kristóf, E, Doan-Xuan, Q-M, Sárvári, A K, Klusóczki, Á, Fischer-Posovszky, P, Wabitsch, M, Bacso, Z, Bai, P, Balajthy, Z, Fésüs, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290354/
https://www.ncbi.nlm.nih.gov/pubmed/27898069
http://dx.doi.org/10.1038/tp.2016.230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290354/
https://www.ncbi.nlm.nih.gov/pubmed/27898069
http://dx.doi.org/10.1038/tp.2016.230

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