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Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain

Kindlins co-activate integrins alongside talin. They possess, like talin, a FERM domain (4.1-erythrin–radixin–moiesin domain) comprising F0–F3 subdomains, but with a pleckstrin homology (PH) domain inserted in the F2 subdomain that enables membrane association. We present the crystal structure of mu...

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Detalles Bibliográficos
Autores principales:	Ni, Tao, Kalli, Antreas C., Naughton, Fiona B., Yates, Luke A., Naneh, Omar, Kozorog, Mirijam, Anderluh, Gregor, Sansom, Mark S.P., Gilbert, Robert J.C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290484/ https://www.ncbi.nlm.nih.gov/pubmed/27974389 http://dx.doi.org/10.1042/BCJ20160791

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