BARD1 nonsense variant c.1921C>T in a patient with recurrent breast cancer

One of the strongest risk factors predisposing patients to breast cancer is a positive family history. In our study, we describe a patient diagnosed with multiple breast cancer tumors. Genetic analysis revealed a pathogenic variant in BARD1, which is associated with an increased risk of developing c...

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Detalles Bibliográficos
Autores principales: Gass, Jennifer, Tatro, Madeline, Blackburn, Patrick, Hines, Stephanie, Atwal, Paldeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290515/
https://www.ncbi.nlm.nih.gov/pubmed/28174632
http://dx.doi.org/10.1002/ccr3.793
Descripción
Sumario:One of the strongest risk factors predisposing patients to breast cancer is a positive family history. In our study, we describe a patient diagnosed with multiple breast cancer tumors. Genetic analysis revealed a pathogenic variant in BARD1, which is associated with an increased risk of developing certain types of cancer.

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