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Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones
The syntheses and crystal structure of 3-chloro-3-methyl-r-2,c-6-diphenylpiperidin-4-one, C(18)H(18)ClNO, (I), 3-chloro-3-methyl-r-2,c-6-di-p-tolylpiperidin-4-one, C(20)H(22)ClNO, (II), and 3-chloro-3-methyl-r-2,c-6-bis(4-chlorophenyl)piperidin-4-one, C(18)H(16)Cl(3)NO, (III), are described. I...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290544/ https://www.ncbi.nlm.nih.gov/pubmed/28217321 http://dx.doi.org/10.1107/S2056989016020661 |
| _version_ | 1782504653109329920 |
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| author | Arulraj, R. Sivakumar, S. Kaur, Manpreet Thiruvalluvar, A. Jasinski, Jerry P. |
| author_facet | Arulraj, R. Sivakumar, S. Kaur, Manpreet Thiruvalluvar, A. Jasinski, Jerry P. |
| author_sort | Arulraj, R. |
| collection | PubMed |
| description | The syntheses and crystal structure of 3-chloro-3-methyl-r-2,c-6-diphenylpiperidin-4-one, C(18)H(18)ClNO, (I), 3-chloro-3-methyl-r-2,c-6-di-p-tolylpiperidin-4-one, C(20)H(22)ClNO, (II), and 3-chloro-3-methyl-r-2,c-6-bis(4-chlorophenyl)piperidin-4-one, C(18)H(16)Cl(3)NO, (III), are described. In each structure, the piperidine ring adopts a chair conformation and dihedral angles between the mean planes of the phenyl rings are 58.4 (2), 73.5 (5) and 78.6 (2)° in (I), (II) and (III), respectively. In the crystals, molecules are linked into C(6) chains by weak N—H⋯O hydrogen bonds and C—H⋯π interactions are also observed. |
| format | Online Article Text |
| id | pubmed-5290544 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2017 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-52905442017-02-17 Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones Arulraj, R. Sivakumar, S. Kaur, Manpreet Thiruvalluvar, A. Jasinski, Jerry P. Acta Crystallogr E Crystallogr Commun Research Communications The syntheses and crystal structure of 3-chloro-3-methyl-r-2,c-6-diphenylpiperidin-4-one, C(18)H(18)ClNO, (I), 3-chloro-3-methyl-r-2,c-6-di-p-tolylpiperidin-4-one, C(20)H(22)ClNO, (II), and 3-chloro-3-methyl-r-2,c-6-bis(4-chlorophenyl)piperidin-4-one, C(18)H(16)Cl(3)NO, (III), are described. In each structure, the piperidine ring adopts a chair conformation and dihedral angles between the mean planes of the phenyl rings are 58.4 (2), 73.5 (5) and 78.6 (2)° in (I), (II) and (III), respectively. In the crystals, molecules are linked into C(6) chains by weak N—H⋯O hydrogen bonds and C—H⋯π interactions are also observed. International Union of Crystallography 2017-01-06 /pmc/articles/PMC5290544/ /pubmed/28217321 http://dx.doi.org/10.1107/S2056989016020661 Text en © Arulraj et al. 2017 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.http://creativecommons.org/licenses/by/2.0/uk/ |
| spellingShingle | Research Communications Arulraj, R. Sivakumar, S. Kaur, Manpreet Thiruvalluvar, A. Jasinski, Jerry P. Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title | Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title_full | Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title_fullStr | Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title_full_unstemmed | Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title_short | Crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| title_sort | crystal structures of three 3-chloro-3-methyl-2,6-diarylpiperidin-4-ones |
| topic | Research Communications |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290544/ https://www.ncbi.nlm.nih.gov/pubmed/28217321 http://dx.doi.org/10.1107/S2056989016020661 |
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