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Crystal structure of (1R,3aR,7aR)-1-{(S)-1-[(2R,5S)-5-(3-hydroxypentan-3-yl)tetrahydrofuran-2-yl]ethyl}-7a-methyl-2,3,3a,4,5,6,7,7a-octahydro-1H-inden-4-one
The title compound, C(21)H(36)O(3), contains an oxolane ring, and six defined stereocentres and may serve as a useful synthon for the synthesis of calcitriol analogues. The configurations of the chiral C atoms of the side chain were unambiguously established in the refinement. In the crystal, C—H⋯O...
Autores principales: | Martínez, Andrea, Santalla, Hugo, Garrido, Fátima, Barry, Aliou Hamady, Gaye, Mohamed, Fall Diop, Yagamare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290546/ https://www.ncbi.nlm.nih.gov/pubmed/28217323 http://dx.doi.org/10.1107/S2056989016020648 |
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