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Arginase-I enhances vascular endothelial inflammation and senescence through eNOS-uncoupling
BACKGROUND: Augmented arginase-II (Arg-II) is implicated in endothelial senescence and inflammation through a mutual positive regulatory circuit with S6K1. This study was conducted to investigate whether Arg-I, another isoform of arginase that has been also reported to play a role in vascular endoth...
Autores principales: | Zhu, Cuicui, Yu, Yi, Montani, Jean-Pierre, Ming, Xiu-Fen, Yang, Zhihong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290613/ https://www.ncbi.nlm.nih.gov/pubmed/28153047 http://dx.doi.org/10.1186/s13104-017-2399-x |
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