Classifying kinase conformations using a machine learning approach

BACKGROUND: Signaling proteins such as protein kinases adopt a diverse array of conformations to respond to regulatory signals in signaling pathways. Perhaps the most fundamental conformational change of a kinase is the transition between active and inactive states, and defining the conformational f...

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Detalles Bibliográficos
Autores principales: McSkimming, Daniel Ian, Rasheed, Khaled, Kannan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290640/
https://www.ncbi.nlm.nih.gov/pubmed/28152981
http://dx.doi.org/10.1186/s12859-017-1506-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290640/
https://www.ncbi.nlm.nih.gov/pubmed/28152981
http://dx.doi.org/10.1186/s12859-017-1506-2

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